Semantic Laboratories
Solutions for Drug Discovery Research Intelligence

 info@semanticlaboratories.com
La Jolla, CA

Service: Establish Computing Platforms

Bioinformatics, cheminformatics and pharmacoinformatics provide the foundation informatics platforms for the integration and analysis of core drug discovery research data.  Both commercial vendor and academic solutions exist to address the unique analysis requirements for an organization.  Selecting and integrating these components requires an in-depth understanding of the organizations research requirements as well as an understanding of the computing infrastructure required to host and integrate these solutions.  Making all of these tools available within a common access framework can be achieved with proper planning and the appropriate infrastructure.

Potential bioinformatics platforms for evaluation include:

  • The Invitrogen Vector NTI platform for DNA and protein sequence analysis

  • The Accelrys Discovery Studio SeqStore/Gene platform for enterprise management of bioinformatics data

  • The Rosetta Resolver platform for management and analysis of large-scale microarray data

  • The Spotfire functional genomics platform for microarray data statistical analysis

  • The GeneCodes DNA Sequencher system for DNA sequence assembly

  • The Tripos Structural Biology platform for protein structure determination and analysis

  • The Accelrys Modeling platform for protein structure determination and analysis

  • Open source and freely available bioinformatics software for BLAST analysis, gene identification, protein sequence analysis, protein function analysis, microarray data analysis etc.

Potential cheminformatics platforms for evaluation include:

  • The MDL ISIS, Direct, Inventory and AssayExplorer platforms for creating, analyzing and managing HTS and chemistry related data

  • The CambridgeSoft ChemOffice, ORACLE Cartridge, Inventory and BioAssay platforms for creating, analyzing and managing HTS and chemistry related data

  • The IDBS ActivityBase, chemXtra and Inventory platforms for creating, analyzing and managing HTS and chemistry related data

  • The Accelrys ACCORD, HTS, Inventory and ORACLE Cartridge platforms for creating, analyzing and managing HTS and chemistry related data

  • The Tripos SYBL platform for computational chemistry and molecular modeling

  • The Chemical Computing Group's Molecular Operating Environment platform for computational chemistry and modeling

  • The Spotfire lead compound platform for HTS and chemistry data visualization

  • The Scitegic Pipeline Pilot workflow development platform for compound library design and HTS data analysis

  • Open source cheminformatics software for computing chemical properties, docking, virtual screening, etc.

Potential pharmacoinformatics platforms for evaluation include:

  • PK Solutions platform for pharmacokinetic data analysis

  • The GraphPad PRISM platform for pharmacology data curve-fitting analysis

  • The JMP statistical software platform of data modeling and design of experiments (DOE)

  • The GeneGo Metadrug platform for predicting drug metabolism and toxicity of compounds

  • The Iconix Drug Matrix platform for assessing potential compound toxicity and side effects

  • Open source and public resources for pharmacogenomics and pharmacogenetics data and analysis

Semantic Laboratories provides research computing platform planning for an organization that addresses current and planned requirements for data analysis.

Additional info:

 
Request additional information from info@semanticlabories.com